Comparison of antibody production, lymphocyte stimulation, and protection induced by four commercial Mycoplasma hyopneumoniae bacterins
نویسنده
چکیده
Methods: Five groups (n=10) of 2-week-old crossbred pigs with no antibodies to M. hyopneumoniae were vaccinated with one of four commercial M. hyopneumoniae bacterins or with saline at 3 and 5 weeks of age. Lymphocyte stimulation assays and serum antibody concentrations were measured on –7, 28, and 45 post vaccination days (PVD). The pigs were challenged with M. hyopneumoniae strain 11 on PVD 51 and necropsied on PVD 78.
منابع مشابه
MLVA typing of Mycoplasma hyopneumoniae bacterins and field strains
Because of the lack of information about both the genetic characteristics of Mycoplasma hyopneumoniae commercial vaccines and their relationship with field strains, the authors attempted to identify genetic subtypes of some M hyopneumoniae bacterins, and to compare them with M. hyopneumoniae field strains. Six commercial M hyopneumoniae bacterins and 28 bronchoalveolar lavages from pigs at slau...
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Mycoplasma hyopneumoniae causes enzootic pneumonia that primarily affects growing pigs. Although the disease is nonfatal, it causes substantial losses attributable to reduced growth performance, increased susceptibility to secondary bacterial pneumonia, and potentiation of PRRSV-induced pneumonia (1, 2). Both cell-mediated and humoral immune responses appear to be important in providing protect...
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